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SINGAPORE - Veterinary technician Annie, in her 30s, got her first tattoo about seven years ago.
She was eventually diagnosed with an eye inflammation linked to a delayed immune reaction against tattoo ink. Read more at straitstimes.com.
HANOI: Vietnam's southern hub Ho Chi Minh City has launched free health check-ups for residents aged 18 and above at 168 health stations on Friday (April 17), local daily VnExpress reported.
A surprising new study suggests that eating a very healthy diet—packed with fruits, vegetables, and whole grains—might be linked to a higher risk of lung cancer in younger non-smokers. Researchers found that patients under 50 diagnosed with lung cancer often had better-than-average diets, raising the possibility that pesticide exposure from conventionally grown produce could be a hidden culprit.
A surprising new study suggests that eating a very healthy diet—packed with fruits, vegetables, and whole grains—might be linked to a higher risk of lung cancer in younger non-smokers. Researchers found that patients under 50 diagnosed with lung cancer often had better-than-average diets, raising the possibility that pesticide exposure from conventionally grown produce could be a hidden culprit.
Pharmacist warns that dark stripes and other toenail changes can signal health problems - from nutrient deficiencies to skin cancer - and urges people to check their feet regularly
The low-density lipoprotein receptor-related protein 2 (LRP2) is an endocytic receptor implicated in the homeostasis of multiple organs. While the low-density lipoprotein receptor-related protein-associated protein 1 (LRPAP1) interacts with LRP2, its regulatory role remains elusive. Past studies showed that a single LRPAP1 molecule binds to LRP2 via complement-type repeats. However, many domains of this kind appear unoccupied in LRP2 within the complex. Here, we investigate if multiple LRPAP1 copies could bind the receptor. Using an integrative structural approach, we characterise the human recombinant LRP2 extracellular domain and its complex with LRPAP1, by identifying three additional LRPAP1 binding sites. Notably, two of these sites overlap with ligand-binding regions, suggesting that LRPAP1 may regulate LRP2 ligand-binding activity. Furthermore, we highlight LRPAP1-LRP2 interaction sites unique within the receptor's family and pathogenic LRP2 mutations located at LRP2-LRPAP1 interfaces. Overall, our study redefines the landscape of the LRP2-LRPAP1 interaction, providing insights into its clinical and functional role. Structural studies of the human LRP2-LRPAP1 complex reveal that multiple LRPAP1 molecules can bind to the receptor, highlighting new binding sites that may control how LRP2 binding to other ligands is regulated in health and disease
South Korean actress Jin Seo-yeon, who drew widespread attention for shedding 28 kg in just 40 days, has shared the overnight oats recipe she uses as her daily breakfast to maintain her figure. - VnExpress International
National Infertility Awareness Week highlights expert backed facts on egg freezing and IVF, debunking common fertility myths to help women make informed choices
The discovery of the foot-and-mouth virus in a pig unit is changing the situation in Cyprus, raising new concerns about how foot-and-mouth disease may develop.